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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Phorbol dibutyrate; PDBu
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
37558-16-0
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2664.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥800.0 |
| 规格： | 5 mg | 产品价格： | ￥2400.0 |
| 规格： | 10 mg | 产品价格： | ￥4000.0 |
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Phorbol 12,13-dibutyrate
CAS No. : 37558-16-0
MCE 国际站：Phorbol 12,13-dibutyrate
产品活性：Phorbol 12,13-dibutyrate (Phorbol dibutyrate) 是一种 PKC 激活剂和有效的皮肤肿瘤启动子。
研究领域：Epigenetics | TGF-beta/Smad
作用靶点：PKC
In Vitro: Phorbol 12,13-dibutyrate (Phorbol dibutyrate) (1 mM) activates PKC and inhibited Na/K-ATPase transport activity in OK cells.
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文献和实验The term phorbol is loosely used to describe a family of naturally occurring compounds referred to as tiglian diterpenes. These are widely distributed in the plant species of the families Euphorbiaceae and Thymelaeaceae. This chapter
致癌助催剂（promoter）。系从大戟科（Euphorbiaceae）植物巴豆（Croton tiglium）种子搾取获得的巴豆油中所含的促致癌活性成分。也称为TPA（12-0-四癸酰基佛博尔13-乙酸）或PMA（佛博尔豆蔻乙酸）。
Cultivation of Normal Human Epidermal Melanocytes in the Absence of Phorbol Esters
skin, was initially achieved by suppressing the growth of keratinocytes and fibroblasts in epidermal cell suspensions with the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate (TPA) and the intracellular cyclic adenosine 3’ , 5’ monophosphate (cAMP
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