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- 详细信息
- 技术资料
- 英文名:
Recombinant Murine IFN-γ
- 保质期:
2年
- 供应商:
上海瓦兰生物
- 保存条件:
-20°
- 库存:
大量
- 规格:
20µg
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手 机:15601775891
Q Q:1597844312
如需订购请联系24小时为您服务:
公司电话:021-61507986
手 机:15601775891
Q Q:1597844312
Recombinant Murine IFN-γ
产品编号:
315-05
别名:
Immune Interferon,type II interferon,T cell interferon,MAF
描述:
IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
氨基酸序列:
MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
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Recombinant Murine IFN-γ,鼠类的IFN-γ重组
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