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- 详细信息
- 文献和实验
- 技术资料
- 库存:
56
- 英文名:
Recombinant Human soluble CD40 Ligand
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
10μg
特别提示:包括重组人sCD40 Ligand在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人sCD40 Ligand
英文名称:Recombinant Human soluble CD40 Ligand
产品货号:GS4380
产品规格:10μg
分子量:Approximately 16.3kDa,a single non-glycosylated polypeptide chain containing 149 amino acids.
储存条件:冷冻(-20℃)
概述
CD40 ligand is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF family and can be cleaved into two chains:the CD40 ligand membrane form and CD40 ligand soluble form.It is primarily expressed on activated CD4+ T lymphocytes,and also found in other types of cells,like NK cells,mast cells,basophils and eosinophils.In total CD40 ligand has three binding partners:CD40,α5β1 integrin and αIIbβ3.It mediates a range of activities on B cells including induction of activation-associated surface antigen,entry into cell cycle,isotype switching and Ig secretion and memory generation.CD40-CD40Linteraction also plays important roles in monocyte activation and dendritic cell maturation.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.0. |
| 内毒素 | Less than 1 EU/μg of rHusCD40Las determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL |
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大鼠sCD40配体(sCD40 Ligand)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠 sCD40 配体 (sCD40 Ligand)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 sCD40 Ligand 单抗包被于酶标板上,标准品和样品中的 sCD40 Ligand 与单抗结合,加入
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