产品货号:jlcR2547 英文名称 :GRO gamma 中文名称 :生长调节致癌基因gamma/GROγ抗体 别 名 :growthregulated oncogene gamma; Chemokine (CXC motif) ligand 3; Cinc 2; Cinc2; CINC2b; CXCL 3; CXCL3; Cytokine induced neutrophil chemoattractant 2; Dcip1; Dendritic cell inflammatory protein 1; Gm1960; GRO3; GRO3 oncogene; GROG; Growth regulated protein gamma; Macrophage inflammatory protein 2 beta precursor; Melanoma growth stimulatory activity gamma; MGSA gamma; MIP 2b; MIP2B; SCYB3; CXCL3_HUMAN. 研究领域 :肿瘤 免疫学 生长因子和激素 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 : Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 产品应用 :WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :12kDa 细胞定位 :分泌型蛋白 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human GRO gamma:35-107/107 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : Growth Regulated Protein gamma (GRO gamma) is a cytokine that may play a role in inflammation and affects endothelial cells in an autocrine fashion. It belongs to the intercrine alpha family (small cytokine c-x-c) (chemokine cxc).
Function: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Subcellular Location: Secreted.
Post-translational modifications: N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Similarity: Belongs to the intercrine alpha (chemokine CxC) family.
SWISS: P19876
Gene ID: 2921
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.