Fadd ELISA Kit| Mouse FAS-ass
ociated death domain protein ELISAFadd ELISA试剂盒| Mouse FAS-associated death domain protein ELISA- ￥2980
- LSM Bio
- 78-5000pg/ml
- 39pg/ml
- 进口
- EF014881
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
50
- 供应商：
LSM BIO
- 检测范围：
78-5000pg/ml
- 检测方法：
夹心法ELISA
- 应用：
检测小鼠血清，血浆，组织匀浆内的目标蛋白含量
- 适应物种：
小鼠
- 标记物：
Fadd
- 样本：
小鼠血清，血浆，组织匀浆
- 灵敏度：
39pg/ml
- 规格：
96Tests
Mouse Fadd ELISA Kit
Catalog EF014881
Packing 48Tests/96Tests
ELISA Method Sandwich ELISA Species Mouse
Sample Mouse serum, plasma, tissue homogenates and other biological fluids and Recombinant Fadd
Detect Range 78-5000pg/ml sensitivity 46.9pg/ml
ELISA Intend Use
Mouse Fadd ELISA Kit is a Sandwich ELISA KIT detecting the concentration of FAS-associated death domain protein in Mouse serum, plasma, tissue homogenates and other biological fluids.
(ELISA KIT is only for Research Only, not for the diagnostic Use!)
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文献和实验带有死亡结构域的Fas 结合蛋白 带有死亡结构域的Fas结合蛋白(Fas-associating protein with death domain，FADD)是分子质量为23kDa的胞质蛋白质。人类FADD基因编码区长约2．6kb，有2个外显子，其间被一长约2kb的内含子分隔。外显子1长286bp，编码N端诱导细胞凋亡所必须的死亡效应结构域(deatheffectdomain，DED)；外显子2长341bp，编码死亡结构域(DD)，此DD基因与Fas
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
years. For the CD95 and the TRAIL-R1/R2 DISCs, it is now clear that the adaptor protein Fas-associated DD protein (FADD) forms part of these complexes and is necessary for recruitment of the pro-apoptotic signaling molecules caspase-8 and caspase
内的死亡域（DD）结合Fas结合蛋白FADD（fas associated protein with DD），FADD再以其N端的死亡效应子域（death effector domain，DED）结合Pro-Caspase-8（或-10），形成一个由Fas-FADD-Pro-Caspase-8（或-10）三种分子组成的复合体，称为诱导死亡的信号复合体（death inducing signaling complex，DISC），其中Pro-Caspase-8（或-10）就可以自身催化
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