- ￥2980
- LSM Bio
- 78-5000pg/ml
- 39pg/ml
- 进口
- ELI-39211m
- 2026年03月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
10
- 供应商：
LSM BIO
- 检测范围：
78-5000pg/ml
- 检测方法：
夹心法ELISA
- 应用：
检测小鼠血清，血浆，组织匀浆内的目标蛋白含量
- 适应物种：
小鼠
- 标记物：
Histone acetyltransferase KAT2B, Kat2b
- 样本：
小鼠血清，血浆，组织匀浆
- 灵敏度：
39pg/ml
- 规格：
96Tests
Mouse Histone acetyltransferase KAT2B, Kat2b ELISA KIT
Product Name:Mouse Histone acetyltransferase KAT2B, Kat2b ELISA KIT
Packing:96T
Catalog No.:ELI-39211m
Gene Name:Mouse Kat2b
Detect Range:78.1-5000pg/ml
Sensitivity:46.875pg/ml
Target Protein Name:Mouse Kat2b
Alternative Name:Mouse Histone acetyltransferase KAT2B, Kat2b
Sample type:serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
ELISA type:Sandwich ELISA Kit
Product Description:Mouse Histone acetyltransferase KAT2B, Kat2b ELISA KIT allows for the in vitro quantitative determination of Mouse Kat2b concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
ELISA Test Principle:
The microtiter plate provided in Mouse Histone acetyltransferase KAT2B, Kat2b ELISA KIT has been pre-coated with an Mouse Histone acetyltransferase KAT2B, Kat2b antibody specific to Mouse Kat2b .Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for Mouse Kat2b and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Mouse Kat2b , biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm.The concentration of Mouse Kat2b in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NOTE:FOR RESEARCH USE ONLY; NOT FOR THERAPEUTIC OR DIAGNOSTIC APPLICATIONS! PLEASE READ ENTIRE PROCEDURE!
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文献和实验HDAC（Histone Deacetylase）组蛋白去乙酰化酶活性测定及药物筛选方案
acetyltransferase, HAT）和组蛋白去乙酰化酶（histone deacetylase, HDAC）共同调控。HAT将乙酰辅酶A的乙酰基转移到组蛋白氨基末端特定的赖氨酸残基上，HDAC使组蛋白去乙酰化，与带负电荷的DNA紧密结合，染色质致密卷曲，基因的转录受到抑制。 在癌细胞中,HDAC的过度表达导致乙酰化作用的增强，通过恢复组蛋白正电荷, 从而增加DNA与组蛋白之间的引力, 使松弛的核小体变得十分紧密, 不利于特定基因的表达, 包括一些肿瘤抑制基因。组蛋白去乙酰化酶抑制剂（histone
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