Low-density lipoprotein recept
or, Ldlr ELISA KIT/ Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒- ￥2980
- LSM Bio
- 78-5000pg/ml
- 39pg/ml
- 进口
- ELI-03224m
- 2026年01月29日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
20
- 供应商：
LSM BIO
- 检测范围：
78-5000pg/ml
- 检测方法：
夹心法ELISA或竞争法ELISA
- 应用：
检测小鼠血清，血浆，组织匀浆内的目标蛋白Low-density lipoprotein receptor, Ldlr含量
- 适应物种：
小鼠
- 标记物：
Low-density lipoprotein receptor, Ldlr
- 样本：
小鼠血清，血浆，组织匀浆及其他生物样本
- 灵敏度：
39pg/ml
- 规格：
96Tests
Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒
Product Name: Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒
Product Name: Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒
Gene Name: Mouse Low-density lipoprotein receptor, Ldlr
Detect Range:78-5000pg/ml
Sensitivity:39pg/ml
Target Protein Name: Mouse Low-density lipoprotein receptor, Ldlr
Alternative Name: Mouse Low-density lipoprotein receptor, Ldlr
ELISA type:Sandwich ELISA Kit
ELISA Test Principle:
NOTE:FOR RESEARCH USE ONLY; NOT FOR THERAPEUTIC OR DIAGNOSTIC APPLICATIONS! PLEASE READ ENTIRE PROCEDURE!
Sample type:serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
Product Description: Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒 allows for the in vitro quantitative determination of Mouse Low-density lipoprotein receptor, Ldlr concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
The microtiter plate provided in Mouse Low-density lipoprotein receptor, Ldlr ELISA试剂盒 has been pre-coated with an Mouse Low-density lipoprotein receptor, Ldlr antibody specific to Mouse Low-density lipoprotein receptor, Ldlr .Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for Mouse Low-density lipoprotein receptor, Ldlr and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Mouse Low-density lipoprotein receptor, Ldlr , biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm.The concentration of Mouse Low-density lipoprotein receptor, Ldlr in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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文献和实验Methods for Studying Rodent Intestinal Lipoprotein Production and Metabolism
. Clin. Invest. 47:1015‐1025. Tso, P., Drake, D.S., Black, D.D., and Sabesin, S.M. 1984. Evidence for separate pathways of chylomicron and very low‐density lipoprotein assembly
一些受体的降解，在胆固醇和脂肪酸的代谢中起到重要作用。 Pcsk9能与肝细胞表面低密度脂蛋白受体 (low density lipoprotein receptor, LDLR) 结合, 构成复合物并靶向转运到溶酶体内进行降解, 从而阻断LDLR在细胞膜表面的循环途径, 抑制低密度脂蛋白胆固醇 (low density lipoproteincholesterol, LDL-C) 通过LDLR转运从体内清除代谢, 使得血浆中LDL-C升高, 最终导致动脉
Models and Analysis of Atherosclerosis, Restenosis, and Aneurysm Formation in the Mouse
Daugherty, A. and Cassis, L. 1999. Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor ‐/‐ mice. Ann. N.Y. Acad. Sci. 892:108‐118.
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