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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
187
- 克隆性:
单克隆
- 保质期:
1年
- 抗体英文名:
CCL15
- 抗体名:
巨噬细胞炎性蛋白15
- 适应物种:
人/动物/植物
- 应用范围:
WB,ELISA等
- 浓度:
1mg/ml
- 保存条件:
-20 °
- 规格:
100ul/200ul
| 规格: | 100ul | 产品价格: | ¥1580.0 |
|---|---|---|---|
| 规格: | 200ul | 产品价格: | ¥2480.0 |
英文名称 : CCL15
中文名称 : 巨噬细胞炎性蛋白15
别 名 : C-C motif chemokine 15; Small inducible cytokine A15; CC chemokine 3; CCL15; Chemokine CC2; HCC2; HMRP2B; CCL15_HUMAN; Leukotactin 1; Macrophage inflammatory protein 5; LKN1; MIP1 delta; MIP1d; MIP5; MIP 5; MIP-5; Mrp2b; NCC3; SCYA15; SCYL3; SY15.
研究领域 : 细胞生物 免疫学 转录调节因子
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 10kDa
细胞定位 : 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human CCL15:31-113/113
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍background:
This gene, chemokine (C-C motif) ligand 15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene, chemokine (C-C motif) ligand 14, and are represented as GeneID: 348249. [provided by RefSeq].
Function:
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Tissue Specificity:
Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
Similarity:
Belongs to the intercrine beta (chemokine CC) family.
SWISS:
Q16663
Gene ID:
6359
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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