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- gelatins
- jlcR2627
- 国内
- 2025年07月13日
- WB,ELISA等
- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
134
- 克隆性：
单克隆
- 保质期：
1年
- 抗体英文名：
IL28A
- 抗体名：
白细胞介素28A抗体
- 适应物种：
人/动物/植物
- 应用范围：
WB,ELISA等
- 浓度：
1mg/ml
- 保存条件：
-20 °
- 规格：
100ul/200ul
| 规格： | 100ul | 产品价格： | ¥1580.0 |
|---|---|---|---|
| 规格： | 200ul | 产品价格： | ¥2480.0 |
产品货号 : jlcR2627
英文名称 : IL28A
中文名称 : 白细胞介素28A抗体
别 名 : Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; EG330496; Ifnl2; IFNL2_HUMAN.
研究领域 : 细胞生物 免疫学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Dog, Pig, Cow, Horse,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 20kDa
细胞定位 : 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human IL-28A:131-200/200
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Function:
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
Subcellular Location:
Secreted.
Similarity:
Belongs to the lambda interferon family.
SWISS:
Q8IZJ0
Gene ID:
282616
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
英文名称 : IL28A
中文名称 : 白细胞介素28A抗体
别 名 : Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; EG330496; Ifnl2; IFNL2_HUMAN.
研究领域 : 细胞生物 免疫学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Dog, Pig, Cow, Horse,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 20kDa
细胞定位 : 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human IL-28A:131-200/200
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Function:
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
Subcellular Location:
Secreted.
Similarity:
Belongs to the lambda interferon family.
SWISS:
Q8IZJ0
Gene ID:
282616
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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文献和实验相关实验
白细胞介素 IL-28 IL-28主要产生细胞：表达于病毒感染的单个核细胞等 IL-28氨基酸数目：200(1L-28A)；198(1L-28B) IL-28受体：IL-28Rα；IL-10Rβ IL-28主要生物学活性：1L-28A和IL-28B均属I型干扰素家族成员，又分别称为IFNb2和IFNi-3。IL-28A与IL-29有81％同源性，其作用为保护细胞抵抗病毒感染，但无抗病毒增殖活性
白细胞介素 IL-30 IL-30主要生物学活性：是IL-27亚基p28的新名称
9175251.59 10165651.11 4.31白细胞介素一2试剂盒中标准品为重组白细胞介素-2，用于体内或细胞培养中自细胞介素-2的测定。现用于制剂中的重组白细胞介素一2的测定，结果证明是可行的。RIA是一种具有高灵敏度、精确度和特异性的体外超微量分析法，技术要求高，影响因素较多。本实验样品结果值的相对标准偏差在理论误差范围内。非特异性结合率（NSB/T）4.28%，试剂盒的重复性和精密度不很理想可以影响相标准偏差的结果[1]。重组人IL-2粉针剂以活性单位标示剂量，而不是以重量单位mg或g表示
白细胞介素28A抗体
¥1580 - 2480
