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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
133
- 克隆性:
单克隆
- 保质期:
1年
- 抗体英文名:
IL23 P19
- 抗体名:
白细胞介素23P19抗体
- 适应物种:
人/动物/植物
- 应用范围:
WB,ELISA等
- 浓度:
1mg/ml
- 保存条件:
-20 °
- 规格:
100ul/200ul
| 规格: | 100ul | 产品价格: | ¥1580.0 |
|---|---|---|---|
| 规格: | 200ul | 产品价格: | ¥2480.0 |
英文名称 : IL23 P19
中文名称 : 白细胞介素23P19抗体
别 名 : alpha subunit P19; IL-23 subunit alpha; IL-23-A; IL-23p19; IL23; IL23 P 19; IL23A; IL23A_HUMAN; IL23P19; interleukin 23 alpha subunit p19; interleukin 23 P19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T cell activation; MGC79388; P19; SGRF.
研究领域 : 细胞生物 免疫学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 19kDa
细胞定位 : 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human IL23 P19:51-150/189
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
Function:
Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Subcellular Location:
Secreted. Secreted upon association with IL12B.
Tissue Specificity:
Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
Q9NPF7
Gene ID:
51561
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片
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文献和实验小鼠白介素-23 p19(IL-23 p19)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 小鼠白介素-23 p19 (IL-23 p19)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗小鼠 IL-23 p19 单抗包被于酶标板上,标准品和样品中的 IL-23 p19
白细胞介素 IL-23 IL-23主要产生细胞:由树突状细胞在活化后分泌 IL-23氨基酸数目:189/328 IL-23分子质量(kDa):19+-40 IL-23受体:IL-12R61;IL23R IL-23主要生物学活性:由一个19kDa亚基(p19)和IL-12 40kDa亚基组成,p19与IL-6,G-CSF,IL12 35kDa亚基结构相似。IL-23可作用于CD
小鼠白细胞介素23 (IL-23) 酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定小鼠血清,血浆及相关液体样本中白细胞介素23 (IL-23 ) 的含量。 实验原理 : 本试剂盒应用双抗体夹心法测定 标本 中 小鼠白细胞介素23 (IL-23 ) 水平。用纯化的 小鼠白细胞介素23 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 白细胞介素23 ,再与 HRP 标记的 IL-23 抗体











