产品货号 : jlcR10943 英文名称 : IL17E 中文名称 : 白介素-17E抗体 别 名 : IL-25; Interleukin-17E; IL 17E; IL-17E; IL 25; IL25; Interleukin 17E; Interleukin 25; Interleukin17E; Interleukin25; IL25_HUMAN; interleukin-25 isoform 1 precursor; interleukin-25. 研究领域 : 免疫学 抗体来源 : Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, 产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 : 17kDa 细胞定位 : 分泌型蛋白 性 状 : Lyophilized or Liquid 浓 度 : 1mg/ml 免 疫 原 : KLH conjugated synthetic peptide derived from human IL17E:431-434/644 亚 型 : IgG 纯化方法 : affinity purified by Protein A 储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed
产品介绍 : The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Function: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Subcellular Location: Secreted.
Tissue Specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
Similarity: Belongs to the IL-17 family.
SWISS: Q9H293
Gene ID: 64806
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.