Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'- C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc- demanding process with the available zinc supply.
产品描述
anti-ZNF658 antibody is a Rabbit Polyclonal antibody againstZNF658..
建议稀释比例
WB : 1:500-1:5000
IHC
Western blot
fetal human brain tissue were subjected to SDS PAGE followed by western blot with PAab09725( ZNF658 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!)