VEGF抗体| VEGF antibody
货号 PAab09391
蛋白别名 L VEGFA antibody, MVCD1 antibody, Vascular permeability factor antibody, VEGF antibody, VEGF A antibody, VEGFA antibody, VPF
蛋白介绍
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010 ). This antibody can recognize all the isoforms of VEFGA.
产品描述
anti-VEGF antibody is a Rabbit Polyclonal antibody againstVEGF..
建议稀释比例
WB :1:200-1:2000;IP:1:200-1:2000;IF:1:10-1:100;IHC:1:50-1:500
IHC
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab09391( VEGFA Antibody) at dilution of 1:200
Western blot
PC-3 cells were subjected to SDS PAGE followed by western blot with PAab09391(VEGFA antibody) at dilution of 1:800(本抗体仅供体外科研用途,不可用于临床诊断!)
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