- ￥2260
- LSM Bio
- 进口
- PAab09030
- 2025年07月13日
- ELISA,IF,WB,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
transient receptor potential cation channel, subfamily V, member 6
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IF,WB,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
transient receptor potential cation channel, subfamily V, member 6
- 抗体英文名：
anti-TRPV6 antibody,TRPV6 antibody
- 抗体名：
anti-TRPV6 抗体,TRPV6 抗体
- 规格：
100μl
TRPV6抗体| TRPV6 antibody
货号 PAab09030
蛋白别名 ABP/ZF antibody, Calcium transport protein 1 antibody, CaT L antibody, CaT like antibody, CAT1 antibody, CATL antibody, ECAC2 antibody, Epithelial calcium channel 2 antibody, HSA277909 antibody, LP6728 antibody, TRPV6 antibody, ZFAB
蛋白介绍
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)- calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
产品描述
anti-TRPV6 antibody is a Rabbit Polyclonal antibody againstTRPV6..
建议稀释比例
WB:1:500-1:5000;IP:1:200-1:1000;IF:1:10-1:100
IHC
Western blot
human placenta tissue were subjected to SDS PAGE followed by western blot with PAab09030( TRPV6 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验【思路解读】诺奖结果公布了，如何利用这个热点？8 篇高分文章，给你思路！
家族其他成员（如 TRPV4、TRPV6）以及特定疾病的致病机理与 TRPV1 的相关性研究还有待探索深入。 2016 年，我们的华人科学家程亦凡教授就和本次诺奖得主 David Julius 教授作为共同通讯，在 Nature 上发表了一篇题为 TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action 的研究论文。 文章以冷冻电镜技术解析了全长 TRPV1 关闭态和开放态的结构，揭示了 TRPV1 从关键
1, CALM2, CALM3, CAMK2B, CAMK4, CNR1, ITK, MAP2K7, NCK2, PAK1, PPIA, PPP3CB, PPP3CC, PPP3R1, TRPV6, VAV1, VAV2, VAV3. Ligands: CCL2, CSF2, CSF3, IFNA1, IFNB1, IFNG, IL1A, IL1B, IL2, IL3, IL4, IL6, IL8, IL10, IL12A, IL12B, IL13, IRF1, LTA, TGFB1, TNF
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