PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
克隆性:
单克隆
适应物种:
Human,Mouse ,Rat
保质期:
12 month
库存:
50
供应商:
LSM bio
宿主:
Rabbit
应用范围:
ELISA,WB,IHC,IF
浓度:
≥95% as determined by SDS-PAGE
抗体英文名:
anti-TRIM63 antibody,TRIM63 antibody
抗体名:
anti-TRIM63 抗体,TRIM63 抗体
规格:
100μg
TRIM63抗体| TRIM63 antibody
货号 PAab08992
蛋白别名 FLJ32380 antibody, IRF antibody, Iris RING finger protein antibody, MuRF 1 antibody, MURF1 antibody, MURF2 antibody, RING finger protein 28 antibody, RNF28 antibody, SMRZ antibody, TRIM63 antibody, tripartite motif containing 63
蛋白介绍
E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti- hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
产品描述
anti-TRIM63 antibody is a Rabbit Polyclonal antibody againstTRIM63..
建议稀释比例
WB:1:200-1:1000;IHC:1:20-1:200;IF:1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human heart using PAab08992(TRIM63 antibody) at dilution of 1:50
Western blot
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab08992(TRIM63 antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)