- ￥2260
- LSM Bio
- 进口
- PAab08924
- 2025年07月11日
- ELISA,WB,IHC,IF
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原：
TRAF interacting protein
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
TRAF interacting protein
- 抗体英文名：
anti-TRAIP antibody,TRAIP antibody
- 抗体名：
anti-TRAIP 抗体,TRAIP 抗体
- 规格：
100μl
TRAIP抗体| TRAIP antibody
货号 PAab08924
蛋白别名 RNF206 antibody, TRIP
蛋白介绍
E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity) (PubMed:22945920). Involved in response to genotoxic lesions during genome replication. Promotes H2AX and RPA2 phosphorylation after replication-associated DNA damage and assists fork progression at UV-induced replication-blocking lesions during S phase (PubMed:26595769). Has also been proposed to play a role in promoting translesion synthesis by mediating the assembly of 'Lys- 63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity (PubMed:24553286). The function in translesion synthesis is controversial (PubMed:26595769).
产品描述
anti-TRAIP antibody is a Rabbit Polyclonal antibody againstTRAIP..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human testis tissue slide using PAab08924( TRAIP Antibody) at dilution of 1:200
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab08924(TRAIP antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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