PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
克隆性:
单克隆
适应物种:
Human
保质期:
12 month
库存:
50
供应商:
LSM bio
宿主:
Rabbit
应用范围:
ELISA,WB
浓度:
≥95% as determined by SDS-PAGE
抗体英文名:
anti-TOP1MT antibody,TOP1MT antibody
抗体名:
anti-TOP1MT 抗体,TOP1MT 抗体
规格:
100μg
TOP1MT抗体| TOP1MT antibody
货号 PAab08866
蛋白别名
蛋白介绍
Releases the supercoiling and torsional tension of DNA introduced during duplication of mitochondrial DNA by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
产品描述
anti-TOP1MT antibody is a Rabbit Polyclonal antibody againstTOP1MT..