- ￥2262
- LSM Bio
- 进口
- PAab08627
- 2025年07月07日
- ELISA,WB,IHC,IF,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
transcription factor EB
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
transcription factor EB
- 抗体英文名：
anti-TFEB antibody,TFEB antibody
- 抗体名：
anti-TFEB 抗体,TFEB 抗体
- 规格：
100μg
TFEB抗体| TFEB antibody
货号 PAab08627
蛋白别名 BHLHE35
蛋白介绍
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
产品描述
anti-TFEB antibody is a Rabbit Polyclonal antibody againstTFEB..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human renal cell carcinoma using PAab08627(TFEB antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab08627(TFEB antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
""> ""> ""> ""> ""> "">风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验三句话读懂一篇 CNS：饶毅团队揭示幼崽恋母情结的潜在机理；吃鱼为啥有益健康？中国团队找到原因
2023 年 3 月 2 日，美国圣路易斯华盛顿大学医学院心血管研究中心的 Ali Javaheri 团队在 Cell Metabolism 杂志发表研究论文 Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity。 该研究发现持续进行隔日禁食（ADF）会加重阿霉素的心脏毒性，包括心肌萎缩和心脏功能受损，并且证实这一损伤与刺激自噬和溶酶体发生的主要调节因子 TFEB 的过度激活有关，强调了在进行 Dox 化疗时
技术资料暂无技术资料 索取技术资料
