TEA domain family member 1 (SV40 transcriptional enhancer factor)
亚型:
IgG
形态:
liquid
保存条件:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
克隆性:
单克隆
适应物种:
Human, Mouse ,Rat
保质期:
12 month
库存:
50
供应商:
LSM bio
宿主:
Rabbit
应用范围:
ELISA,WB
浓度:
≥95% as determined by SDS-PAGE
抗体英文名:
anti-TEAD1 antibody,TEAD1 antibody
抗体名:
anti-TEAD1 抗体,TEAD1 抗体
规格:
100μg
TEAD1抗体| TEAD1 antibody
货号 PAab08581
蛋白别名 TCF13 antibody, TEF1
蛋白介绍
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
产品描述
anti-TEAD1 antibody is a Rabbit Polyclonal antibody againstTEAD1..
建议稀释比例
IHC
Immunohistochemical of paraffin-embedded human trachea using 13518-1-AP(TEKT2 antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with 13518-1-AP(TEKT2 antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)