- ￥2262
- LSM Bio
- 进口
- PAab08834
- 2025年07月11日
- ELISA,WB,IF
- E. coli - derived recombinant protein
- Human, Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
- 抗体英文名：
anti-TNKS antibody,TNKS antibody
- 抗体名：
anti-TNKS 抗体,TNKS 抗体
- 规格：
100μg
TNKS抗体| TNKS antibody
货号 PAab08834
蛋白别名 PARP5A antibody, PARPL antibody, TIN1 antibody, TINF1 antibody, TNKS1
蛋白介绍
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
产品描述
anti-TNKS antibody is a Rabbit Polyclonal antibody againstTNKS..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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