- ￥2860
- LSM Bio
- 进口
- PAab08831
- 2025年07月13日
- ELISA,WB,IHC,IF,IP
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TNFAIP3 interacting protein 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
TNFAIP3 interacting protein 1
- 抗体英文名：
anti-TNIP1 antibody,TNIP1 antibody
- 抗体名：
anti-TNIP1 抗体,TNIP1 抗体
- 规格：
100μg
TNIP1抗体| TNIP1 antibody
货号 PAab08831
蛋白别名 KIAA0113 antibody, NAF1
蛋白介绍
Inhibits NF-kappa-B activation and TNF-induced NF-kappa- B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti- inflammatory response of macrophages and positively regulates TLR- induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection.
产品描述
anti-TNIP1 antibody is a Rabbit Polyclonal antibody againstTNIP1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human spleen using PAab08831(TNFR2 antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab08831(TNFR2 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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