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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TBC1 domain family, member 5
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
TBC1 domain family, member 5
- 抗体英文名:
anti-TBC1D5 antibody,TBC1D5 antibody
- 抗体名:
anti-TBC1D5 抗体,TBC1D5 抗体
- 规格:
100μg
TBC1D5抗体| TBC1D5 antibody
货号 PAab08515
蛋白别名 KIAA0210
蛋白介绍
May act as a GTPase-activating protein (GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity (PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy (PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes (PubMed:24603492).
产品描述
anti-TBC1D5 antibody is a Rabbit Polyclonal antibody againstTBC1D5..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab08515(TBC1D5 antibody) at dilution of 1:100
Western blot
A431 cells were subjected to SDS PAGE followed by western blot with PAab08515(TBC1D5 antibody) at dilution of 1:400(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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