- ￥2062
- LSM Bio
- CHINA
- PAab06281
- 2025年07月17日
- ELISA,WB,IHC，IF
- Mouse
- Human, Mouse ,Pig
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD274 molecule
- 亚型：
IgG1
- 形态：
liquid
- 保存条件：
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
- 克隆性：
单克隆
- 适应物种：
Human, Mouse ,Pig
- 保质期：
12 month
- 库存：
50
- 供应商：
LSM bio
- 宿主：
Mouse
- 应用范围：
ELISA,WB,IHC，IF
- 浓度：
≥95% as determined by SDS-PAGE
- 抗体英文名：
anti-PD-L1/CD274 antibody,PD-L1/CD274 antibody
- 抗体名：
anti-PD-L1/CD274 抗体,PD-L1/CD274 抗体
- 规格：
100μg
PD-L1/CD274抗体| PD-L1/CD274 antibody
货号 PAab06281
蛋白别名 B7 H antibody, B7 H1 antibody, B7 homolog 1 antibody, B7H1 antibody, CD274 antibody, CD274 molecule antibody, PD L1 antibody, PDCD1 ligand 1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, PD-L1 antibody, PD-L1/CD274 antibody, Programmed death ligand 1
蛋白介绍
Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 kDa, the apparent molecular weight has been reported as 45-70 kDa, suggesting probable glycosylation (PMID: 18760278; 16493058).?
产品描述
anti-PD-L1/CD274 antibody is a Mouse Monoclonal antibody againstPD-L1/CD274..
建议稀释比例
WB:1:500-1:5000;IHC:1:100-1:500;IF:1:50-1:500
IHC
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab06281(PD-L1/CD274 Antibody) at dilution of 1:50 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with PAab06281( PD-L1/CD274 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!)
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