- ￥2262
- LSM Bio
- 进口
- PAab05847
- 2025年07月14日
- ELISA,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
nuclear receptor subfamily 5, group A, member 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
nuclear receptor subfamily 5, group A, member 1
- 抗体英文名：
anti-NR5A1 antibody,NR5A1 antibody
- 抗体名：
anti-NR5A1 抗体,NR5A1 抗体
- 规格：
100μl
NR5A1抗体| NR5A1 antibody
货号 PAab05847
蛋白别名 AD4BP antibody, FTZF1 antibody, SF1
蛋白介绍
Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO- NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phosphatidylcholine (By similarity). Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
产品描述
anti-NR5A1 antibody is a Rabbit Polyclonal antibody againstNR5A1..
建议稀释比例
WB:1:500-1:5000;IP:1:200-1:1000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human liver using PAab05847(NR5A1 antibody) at dilution of 1:100
Western blot
mouse ovary tissue were subjected to SDS PAGE followed by western blot with PAab05847(NR5A1 antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验saturated area over the injection site and the labeled fibers exiting the corpus callosum into the contralateral cortex in the overview image. (B, D ) To enhance this signal, immunohistochemical staining was performed using an antibody directed against EGFP
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