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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
NADPH oxidase 4
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9WVH4
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP,FC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
NADPH oxidase 4
- 抗体英文名:
anti-NOX4 antibody,NOX4 antibody
- 抗体名:
anti-NOX4 抗体,NOX4 抗体
- 规格:
100μl
NOX4抗体| NOX4 antibody
货号 PAab05806
蛋白别名 RENOX
蛋白介绍
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. Isoform 4: Involved in redox signaling in vascular cells. Constitutively and NADPH-dependently generates reactive oxygen species (ROS). Modulates the nuclear activation of ERK1/2 and the ELK1 transcription factor, and is capable of inducing nuclear DNA damage. Displays an increased activity relative to isoform 1.
产品描述
anti-NOX4 antibody is a Rabbit Polyclonal antibody againstNOX4..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab05806( NOX4 Antibody) at dilution of 1:200
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab05806(NOX4 antibody) at dilution of 1:600(本抗体仅供体外科研用途,不可用于临床诊断!) <"">
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