PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
克隆性:
单克隆
适应物种:
Human,Mouse ,Rat
保质期:
12 month
库存:
50
供应商:
LSM bio
宿主:
Rabbit
应用范围:
ELISA,WB,IHC
浓度:
≥95% as determined by SDS-PAGE
抗体英文名:
anti-OAS1 antibody,OAS1 antibody
抗体名:
anti-OAS1 抗体,OAS1 抗体
规格:
100μg
OAS1抗体| OAS1 antibody
货号 PAab05949
蛋白别名 OIAS
蛋白介绍
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
产品描述
anti-OAS1 antibody is a Rabbit Polyclonal antibody againstOAS1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human liver tissue slide using PAab05949( OAS1 Antibody) at dilution of 1:200
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab05949(OAS1 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!)