- ￥2062
- LSM Bio
- 进口
- PAab00311
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
alkB, alkylation repair homolog 1 (E. coli)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9GZT9
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
ALKBH1
- 抗体英文名：
anti-ALKBH1 antibody,ALKBH1 antibody
- 抗体名：
anti-ALKBH1 抗体,ALKBH1 抗体
- 规格：
100μg
ALKBH1抗体| ALKBH1 antibody
货号 PAab00311
蛋白别名 ABH antibody, ABH1 antibody, alkB antibody, ALKBH antibody, ALKBH1 antibody, DNA lyase ABH1 antibody, hABH
蛋白介绍
Dioxygenase that acts as a DNA demethylase (PubMed:18603530). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:18603530). Specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA. N(6)-methyladenosine (m6A) DNA is present at some L1 elements in embryonic stem cells and probably promotes their silencing (By similarity). Also able to repair alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation, but with low activity (PubMed:18603530). Also has DNA lyase activity and introduces double-stranded breaks at abasic sites: cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites (PubMed:19959401). DNA lyase activity does not require alpha-ketoglutarate and iron and leads to the formation of an irreversible covalent protein-DNA adduct with the 5' DNA product (PubMed:19959401, PubMed:23577621). DNA lyase activity is not required during base excision repair and class switch recombination of the immunoglobulin heavy chain during B lymphocyte activation. May play a role in placental trophoblast lineage differentiation (By similarity).
产品描述
anti-ALKBH1 antibody is a Rabbit Polyclonal antibody againstALKBH1..
建议稀释比例
WB :1:200-1:2000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human colon tissue slide using PAab00311( ALKBH1 Antibody) at dilution of 1:50
Western blot
human placenta tissue were subjected to SDS PAGE followed by western blot with PAab00311(ALKBH1 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!)
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文献和实验
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