- ￥2062
- LSM Bio
- 进口
- PAab00273
- 2025年07月08日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat,Zebrafish
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat,Zebrafish
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9GZT9
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
AKT3
- 抗体英文名：
anti-AKT3 antibody,AKT3 antibody
- 抗体名：
anti-AKT3 抗体,AKT3 抗体
- 规格：
100μg
AKT3抗体| AKT3 antibody
货号 PAab00273
蛋白别名 AKT3 antibody, DKFZp434N0250 antibody, PKB GAMMA antibody, PKBG antibody, PRKBG antibody, Protein kinase Akt 3 antibody, Protein kinase B gamma antibody, RAC gamma antibody, RAC PK gamma antibody, STK 2
蛋白介绍
AKT3 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase- dependent apoptosis.
产品描述
anti-AKT3 antibody is a Rabbit Polyclonal antibody againstAKT3..
建议稀释比例
WB :1:200-1:2000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab00273( AKT3 Antibody) at dilution of 1:50
Western blot
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab00273(AKT3 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!)
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文献和实验
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