重组人GH现货供应

特别提示：包括重组人GH在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人GH
英文名称：Recombinant Human Growth Hormone
产品货号：GS4531
产品规格：20μg

分子量：Approximately 22kDa,a single non-glycosylated polypeptide chain containing 191 amino acids
储存条件：冷冻（-20℃）

概述

Growth hormone(GH),also known as somatotropin,is a member of a family of growth factors that includes prolactin,placental lactogens,proliferins,and somatolactin.It is a peptide hormone that stimulates growth,cell reproduction and regeneration in humans and other animals.Growth hormone is a 191-amino acid,single-chain polypeptide that is synthesized,stored,and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone(GHRH)and somatostatin(SST)as well as by signals from the periphery-ghrelin and leptin.The human GH cDNA encodes a 217 amino acid(a.a.)residue precursor protein with a 26 a.a.putative signal peptide.By alternative splicing,at least four isoforms of GH have been identified.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat Nb2-11 lymphoma cells is less than 0.1ng/ml,corresponding to a specific activity of>1.0×107 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution with 5mMNaHCO3,pH 7.0.
内毒素	Less than 1EU/μg of rHuGH as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F

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