重组大鼠TARC/CCL17北京厂家

特别提示：包括重组大鼠TARC/CCL17在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠TARC/CCL17
英文名称：Recombinant Rat Thymus and Activation Regulated Chemokine/CCL17
产品货号：GS4732
产品规格：5μg

分子量：Approximately 8.1kDa,a single non-glycosylated polypeptide chain containing 70 amino acids.
储存条件：冷冻（-20℃）

概述

CCL17 also known as thymus and activation-related chemokine(TARC)is encoded by the CCL17 gene located on the chromosome 16.It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.It plays an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.CCL17 has approximately 24 - 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 0.1 EU/μg of r rRtTARC/CCL17 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	ARATNVGREC CLDYFKGAIP IRKLVTWFRT SVECPKDAIV FETVQGRLIC TDPKDKHVKK AIRHLKNQRL

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