重组小鼠SDF-1β/CXCL12β北京供应商

特别提示：包括重组小鼠SDF-1β/CXCL12β在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠SDF-1β/CXCL12β
英文名称：Recombinant Murine Stromal-Cell Derived Factor-1 beta/CXCL12b
产品货号：GS4532
产品规格：2μg

分子量：Approximately 8.5kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.Murine CXCL12 is expressed as two isoforms that differ only in the C-terminal tail.Both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.SDF-1 is highly conserved between species,murine CXCL12β shares approximately 92%amino acid sequence identity with human CXCL12β.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 50-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素	Less than 1 EU/μg of rMuSDF-1β/CXCL12βas determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM

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