重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)

特别提示：包括重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)
英文名称：Recombinant Human Membrane Primary Amine Oxidase
产品货号：JN0768
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg27-Asn763在C端含有His标签。

VAP-1/AOC3质量控制：＞95%(还原性SDS-PAGE)

VAP-1/AOC3制剂：液体

VAP-1/AOC3保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于VAP-1/AOC3：
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inflammation through its release from intracellular granules in which the protein is stored. The adhesive function of VAP-1 has been demonstrated in studies showing that the protein is important for the adherence of certain lymphocyte subtypes to inflamed endothelial tissues. VAP-1 mediated adhesion is involved in the process of leukocyte extravasation, an important feature of inflammatory responses. VAP-1 is considered to be a therapeutic target for diabetes, oxidative stress, and inflammatory diseases.

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