重组人GRO-γ/CXCL3现货供应

特别提示：包括重组人GRO-γ/CXCL3在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人GRO-γ/CXCL3
英文名称：Recombinant Human Growth Regulated Protein-gamma/CXCL3
产品货号：GS4851
产品规格：2μg

分子量：Approximately 7.9kDa,a single non-glycosylated polypeptide chain containing 73 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL3,also named GRO-γ,is belonging to the CXC chemokine family and encoded by the gene CXCL3.CXCL3/GRO-γ shares 86%amino acid sequence with CXCL1/GRO-α.All three human GROs(GRO-α,GRO-β,GRO-γ)are members of the intercrine alpha(chemokine C-X-C)subfamily of chemokines.This chemokine is secreted by monocytes and macrophages.The functional receptor for CXCL3 has been identified as CXCR2.Similar to other GRO proteins,CXCL3 is potent neutrophil attractants and activators.CXCL3 plays a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.All three GROs can bind with high affinity to the IL-8 receptor type B.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,50 mM NaCl.
内毒素	Less than 1 EU/μg of rHuGRO-γ/CXCL3 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

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