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Anti-DNA G-quadruplex struct,cl BG4
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文献和实验G-Quadruplex Structures and G-Quadruplex-Interactive Compounds
G-quadruplexes are noncanonical secondary structures formed in DNA sequences containing consecutive runs of guanines. DNA G-quadruplexes have recently emerged as attractive cancer therapeutic targets. It has been shown that the 3′ G-rich
Overview of Formation of G‐Quadruplex Structures
‐311. Bates, P.J., Mergny, J.L., and Yang, D. 2007. Quartets in G‐major – The first international meeting on quadruplex DNA. EMBO Rep. 8: 1003‐1010
Quantifying Interactions Between G-Quadruplex DNA and Transition-Metal Complexes
Telomerase inhibition through guanine quadruplex sequestration by small-molecule drugs is of great current interest as an anticancer strategy. G-quadruplexes (GQs) can be formed at the guanine-rich sequences found at the end of the telomere
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