重组人IL-15北京价格

特别提示：包括重组人IL-15在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人IL-15
英文名称：Recombinant Human Interleukin-15
产品货号：GS4875
产品规格：2μg

分子量：Approximately 12.9kDa,a single non-glycosylated polypeptide chain containing 114 amino acids.
储存条件：冷冻（-20℃）

概述

Human Interleukin-15(IL-15)is expressed by the IL15 gene located on the chromosome 4.It shares approximately 97%and 73%sequence identity with simian and murine IL-15,respectively.Both human IL-15 and simian IL-15 are active on murine cells.IL-15 is secreted by mononuclear phagocytes(and some other cells),especially macrophages following infection by virus.It possesses a variety of biological functions,including stimulating and maintaining of cellular immune responses,especially regulating T and natural killer(NK)cell activation and proliferation.In additionally,it shares many biological properties with IL-2,including T,B and NK cell-stimulatory activities.IL-15 signals through a complex composed of IL-2/IL-15 receptor beta chain.Although IL-15 lacks sequence homology with IL-2,it has recently been shown that both the beta and gamma chains of the IL-2 receptor are utilized for IL-15 binding and signaling.In addition,an IL-15 specific binding protein has also been cloned from a mouse T cell clone.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1EU/μg of rHuIL-15 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS

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