重组人瓣状内切核酸酶1(FEN-1)北京现货

特别提示：包括重组人瓣状内切核酸酶1(FEN-1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人瓣状内切核酸酶1(FEN-1)
英文名称：Recombinant Human Flap Endonuclease 1
产品货号：JN1935
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys380表达纯化得来。

FEN-1质量控制：＞95%(还原性SDS-PAGE)

FEN-1制剂：液体

FEN-1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于FEN-1：
Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5-overhanging flap structure and processes the 5 ends of Okazaki fragments for synthesis. FEN1 also exhibits RNase H activity by possessing 5-3 exonuclease activity on gapped double-stranded or nicked DNA, FEN1 is involved in the long patch base excision repair (LP-BER) pathway, it can cleave within the apurinic/apyrimidinic (AP) site-terminated flap. FEN1 can prevent flaps from equilibrating into structures that lead to duplications and deletions. FEN1 is also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

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