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- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1023043-30-2
- 规格:
1 mg/5 mg/10 mg/25 mg
| 规格: | 1 mg | 产品价格: | ¥640.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1600.0 |
| 规格: | 10 mg | 产品价格: | ¥2600.0 |
| 规格: | 25 mg | 产品价格: | ¥4560.0 |
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ATP synthase inhibitor 1
CAS No. : 1023043-30-2
MCE 国际站:ATP synthase inhibitor 1
产品活性:ATP synthase inhibitor 1 是一种 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂,抑制线粒体通透性转换孔的开放,但不影响 ATP 的水平。
研究领域:Membrane Transporter/Ion Channel
作用靶点:ATP Synthase
In Vitro: ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex.
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文献和实验ATP或称F0F1 复合物(F0F1 complexes), 该酶在分离状态下具有ATP水解酶的活性,在结合状态下具有ATP合酶的活性, 属F型ATPase。除了线粒体中有ATP合酶外,植物叶绿体的类囊体和好氧细菌都有ATP合酶的同源物,ATP合酶的分子组成和主要特点是: 头部:头部即F1, 细菌和线粒体ATP合酶的F1都是水溶性的蛋白,结构相似,由5种多肽(α、β、γ、δ和ε)组成的九聚体(α3β3γδε),α亚基和β亚基构成一种球形的排列,头部含有三个催化ATP
Methods to Determine the Status of Mitochondrial ATP Synthase Assembly
The adenosine triphosphate (ATP) synthase (F1 -F0 complex) of the mitochondrial inner membrane is responsible for making nearly all of the ATP utilized by eukaryotic organisms. The enzyme is an oligomer of more than 20 different subunits, 14
1. The recently discovered WYE-125132 and related drugs represent a new generation of ATP competitive and highly specific inhibitors targeting mTOR globally. As mTORC1 and mTORC2 mediate diverse sets of both redundant and distinctive cellular pathways of growth
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