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TK05
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Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
货期:1-2天
MedChemExpress LLC
10 mM * 1 mL/1 mg/5 mg/10 mg
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CAS No. : 1245734-61-5
MCE 国际站:TK05
产品活性:TK05 是一种有效选择性的白三烯 C4 合成酶 (LTC4S) 抑制剂,其 IC50 值为 95 nM。
研究领域:Metabolic Enzyme/Protease
作用靶点:Gutathione S-transferase
In Vitro: TK05 reduces LTC4 production in a dose-dependent manner with an IC50 value of 318 ± 60 nM in MM6 Cells.
In Vivo: TK05 (0.12-6 mg/kg; given i.p.; only once) significantly reduces LTE4 levels.
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