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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期:询盘
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MedChemExpress LLC
- CAS号:
2269494-43-9
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询盘
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VDR agonist 1
CAS No. : 2269494-43-9
MCE 国际站:VDR agonist 1
产品活性:VDR agonist 1 (compound 28) 是一种非甾体类维生素 D 受体 (VDR) 的激动剂, 在MCF-7 细胞中测得其 IC50 值为 690 nM。VDR agonist 1 通过上调 p21 和 p27 的表达来抑制细胞周期,通过增加 BAX 的表达来促进细胞凋亡,降低 Bcl-2 的表达。
研究领域:Vitamin D Related/Nuclear Receptor | Apoptosis
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文献和实验Flow Cytometry Assay to Measure Internalization of GPCRs
onto 6-cm dishes.2) Fill dishes with 2 mL growth media with 30 mM HEPES, pH 7.4. Set aside a dish of 293/B2AR at 4degC. You will use this dish to estimate the total number of receptors on the surface of a sample (i.e. before agonist treatment). HEPES reduces
Flow Cytometry Assay to Measure Internalization of GPCR's
media with 30 mM HEPES, pH 7.4. Set aside a dish of 293/B2AR at 4degC. You will use this dish to estimate the total number of receptors on the surface of a sample (i.e. before agonist treatment). HEPES reduces exposure of the cells to extreme pH values
Flow Cytometry Assay to Measure Internalization of GPCR
at 4degC. You will use this dish to estimate the total number of receptors on the surface of a sample (i.e. before agonist treatment). HEPES reduces exposure of the cells to extreme pH values outside of the incubator. 3) Add agonist to dishes and place
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