FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant Murine FGF-4 is a 19.0 kDa protein consisting of 173 amino acid residues.
Source:E.coli
Synonyms:Fibroblast Growth Factor-4
AA Sequence:APNGTRHAEL GHGWDGLVAR SLARLPVAAQ PPQAAVRSGA GDYLLGLKRL RRLYCNVGIG FHLQVLPDGR IGGVHADTRD SLLELSPVQR GVVSIFGVAS RFFVAMSSRG KLFGVPFFTD ECKFKEILLP NNYNAYESYA YPGMFMALSK NGRTKKGNRV SPTMKVTHFL PRL
Purity:≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 0.4-1.0 ng/ml.