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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
BBS4
- 浓度:
1 mg/mL.
- 应用范围:
WB
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
- 保质期:
1年
- 供应商:
Huabio
- 标记物:
Non-conjugated
- 保存条件:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human BBS4 431-519/519
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2500.0 |
May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
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ER1904-15·Anti-BBS4 Antibody
¥1500 - 2500








