重组人LR3 IGF-1北京品牌

特别提示：包括重组人LR3 IGF-1在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人LR3 IGF-1
英文名称：Recombinant Human LR3 Insulin-like Growth Factor-1
产品货号：GS4548
产品规格：100μg

分子量：Approximately 9.1kDa,a single non-glycosylated polypeptide chain containing 83 amino acids.
储存条件：冷冻（-20℃）

概述

IGF-1 belonged to the insulin gene family,is a mitogenic polypeptide growth factor that stimulate the proliferation and survival of various cell types including muscle,bone,and cartilage tissue in vitro.It is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion.The production of IGF-1 is stimulated by growth hormone(GH)and can be retarded by undernutrition,growth hormone insensitivity,lack of growth hormone receptors,or failures of the downstream signaling pathway post GH receptor including SHP2 and STAT5B.The LR3 IGF-1 is a long-term analog of human IGF-1,specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by the stimulation of protein synthesis using rat L6 myoblasts is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.0.
内毒素	Less than 50 EU/mg of rHuLR3 IGF-1 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA

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