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- 详细信息
- 文献和实验
- 技术资料
- 库存:
310
- 英文名:
Recombinant Rat Stromal-Cell Derived Factor-1 beta/CXCL12β
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
2μg
特别提示:包括重组大鼠SDF-1β/CXCL12β在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组大鼠SDF-1β/CXCL12β
英文名称:Recombinant Rat Stromal-Cell Derived Factor-1 beta/CXCL12β
产品货号:GS4528
产品规格:2μg
分子量:Approximately 8.4kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件:冷冻(-20℃)
概述
CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.Rat CXCL12 is expressed as two isoforms that differ only in the C-terminal tail.And both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.SDF-1 is highly conserved between species,murine CXCL12β shares approximately 96%amino acid sequence identity with human CXCL12β.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 100-200ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rRtSDF-1β/CXCL12β as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM |
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