重组大鼠CDNF价格

特别提示：包括重组大鼠CDNF在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠CDNF
英文名称：Recombinant Rat Cerebral Dopamine Neurotrophic Factor
产品货号：GS4717
产品规格：5μg

分子量：Approximately 18.8kDa,a single non-glycosylated polypeptide chain containing 163 amino acids.
储存条件：冷冻（-20℃）

概述

Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant rat CDNF contains 163 amino acid residues and it shares 84%and 87%a.a.sequence identity with human and murine CDNF.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.It is able to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5 - 25μg/mL on a nitrocellulose-coated microplate.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 0.1 EU/μg of rRtCDNF as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	QGLEAGVRSR ADCEVCKEFL NRFYNSLLTR GIDFSVDTIE EELISFCADT KGKENRLCYY LGATKDSATK ILGEVTRPMS VHMPTVKICE KLKKMDSQIC ELKYEKKLDL ESVDLWKMRV AELKQILHSW GEECRACAEK HDYVNLIKEL APKYVETRPQ TEL

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