- ￥4626
- Exalpha
- 美国
- F105P
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 规格：
250ug
Background
Human herpervirus-8 (HHV-8) cyclin is a component of the HHV-8 virus particle. HHV8 has been found to be associated with three different diseases in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.
Synonyms: HHV8cyclin
Source
Immunogen: Inclusion Bodies from E. Coli expressing his-tagged full length human cyclin G2 protein.
Product
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Ammonium Sulfate Precipitation
Concentration: See vial for concentration
Applications
Applications: Immunoblotting 1-5 ug/ml. Immunoprecipitation 10-20 ug/ml.
Functional Analysis: Immunoprecipitation
Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: room temperature
Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
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文献和实验References
Carbone, A., et al. 'Proliferation in HHV-8-positive primary effusion lymphomas is associated with expression of HHV-8 cyclin but independent of p27(kip1).' Am. J. Pathol. 2000, 156, 1209-1215 Product Specific References: 1. Godfrey, A., et al. 'Inhibiting primary effusion lymphoma by leniviral vectors encoding short hairpin RNA.' Blood, 2005, 105, 2510-2518. 2. Sugaya, M., et al. 'Lymphatic dysfunction in transgenic mice expressing KSHV k-cyclin under the control of the VEGFR-3 promoter.' Blood, 2005, 105, 2356-2363. 3. Jarviluoma, A., et al. 'KSHV viral cyclin binds to p27KIP1 in primary effusion lymphomas.' Blood, 2004, 104, 3349-3354.
Protein Reference(s)
Database Name: UniProt
Accession Number: O40946 (KSHV)
Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
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