重组小鼠ANGPTL4(血管生成素样蛋白4)

特别提示：包括重组小鼠ANGPTL4(血管生成素样蛋白4)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠ANGPTL4(血管生成素样蛋白4)
英文名称：Recombinant Mouse Angiopoietin Like protein 4
产品货号：JN1318
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys167-Ser410在C端带有Fc标签。

ANGPTL4质量控制：＞95%(还原性SDS-PAGE)

ANGPTL4制剂：液体

ANGPTL4保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ANGPTL4：
Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

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