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- Elabscience
- E-AB-70300
- 湖北武汉
- 2025年07月06日
- WB;IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
CASP1 Polyclonal Antibody_货号:E-AB-70300_多克隆抗体
- 抗体英文名：
CASP1 Polyclonal Antibody
- 应用范围：
WB;IHC
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 目录编号：
E-AB-70300
- 级别：
科研级别
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态：
液体
- 亚型：
IgG
- 规格：
200μL/120μL/60μL
| 规格： | 200μL | 产品价格： | ￥3300.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥2220.0 |
| 规格： | 60μL | 产品价格： | ￥1380.0 |
货号：E-AB-70300
| Verified Samples |
Verified Samples in WB:MCF-7,THP-1,Mouse spleen,Mouse thymus,Rat spleen,Rat lung,Rat thymus
Verified Samples in IHC:Human tonsil,Human lung cancer,Human liver cancer |
| Dilution |
WB 1:500-1:2000, IHC 1:300-1:800
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant protein corresponding to Mouse Caspase1
|
| Abbre |
CASP1
|
| Synonyms |
CASP-1;CASP1;CASP1;Caspase 1;Caspase-1 subunit p10;ICE;IL-1 beta-converting enzyme;IL-1BC;IL1 beta converting enzyme;IL1B convertase;Interleukin 1 beta convertase;Interleukin 1B converting enzyme;Interleukin-1 beta convertase;Interleukin-1 beta-converting enzyme;p45抗体
|
| Swissprot |
P29466,P29452,P43527
|
| Calculated MW |
45kDa
|
| Observed MW |
45-47kDa,30kDa,35kDa
|
| Cellular Localization |
Cytoplasm.
|
| Concentration |
1.2 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Cell Biology; Metabolism
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
|
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文献和实验自2012年第一篇引用文献问世，至2023年8月，Elabscience已协助各地科研工作者发表超13,000篇SCI文献，包括行业顶/级期刊Nature Medicine, Nature, Cell, Signal Transduction and Targeted Therapy, Circulation, Molecular Cancer, Immunity, Advanced Materials等，总影响因子（IF）59472.59，其中IF≥30的文献超30篇，最高影响因子为66.849，发文单位包含北京大学、中国科学技术大学、浙江大学、斯坦福大学、耶鲁大学、柏林夏里特大学等国内外各大高校。
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文献详情查看>>>>
Construction of Polyclonal Antibody Libraries Using Phage Display
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