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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Connexin 43 Polyclonal Antibody_货号:E-AB-70097_多克隆抗体
- 抗体英文名:
Connexin 43 Polyclonal Antibody
- 靶点:
Connexin 43
- 浓度:
5 μL/Test
- 应用范围:
WB;IHC
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 级别:
科研
- 库存:
99
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL
| 规格: | 200μL | 产品价格: | ¥3300.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥2220.0 |
| 规格: | 60μL | 产品价格: | ¥1380.0 |
货号:E-AB-70097
| Verified Samples |
Verified Samples in WB:Hela,HepG2,SW480
Verified Samples in IHC:Mouse heart,Rat heart |
| Dilution |
WB 1:1000-1:2000, IHC 1:300-1:800
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
|
| Abbre |
Connexin 43
|
| Synonyms |
Connexin 43;Connexin-43;Cx 43;Cx43;CXA1;DFNB38;Gap junction 43 kDa heart protein;Gap junction alpha-1 protein;Gap junction protein alpha 1 43kDa (connexin 43);Gap junction protein alpha 1 43kDa;Gap junction protein alpha like;GJA 1;Gja1;GJAL;ODD;ODDD;ODOD;SDTY3抗体
|
| Swissprot |
P17302,P23242,P08050
|
| Calculated MW |
43kDa
|
| Observed MW |
43kDa
|
| Cellular Localization |
Cell membrane. Cell junction>gap junction.
|
| Concentration |
0.53 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Cardiovascular; Signal Transduction
|
| Conjugation |
Unconjugated
|
| Background |
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
|
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文献和实验A cigarette filter-derived biomimetic cardiac niche for myocardial infarction repair
IF:18.9
Journal:Bioactive Materials
DOI:10.1016/j.bioactmat.2024.02.012
Analysis of Connexin 43 Expression on Keratinocytes Using Flow Cytometry
of differentiation. Quantitative data for the differential expression of epitopes on single cells can be obtained using a flow cytometer. Simultaneous analysis of two intracellular epitopes, keratin 14 and connexin 43, using flow cytometry after keratinocyte
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
The Use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Alterations in Connexin43 (Cx43) expression levels have been shown to play a role in inflammatory processes including skin wounding and neuroinflammation. Cx43 protein levels increase following a skin wound and can inhibit wound healing
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