重组人PEA15(星形胶质细胞磷酸化蛋白15)

特别提示：包括重组人PEA15(星形胶质细胞磷酸化蛋白15)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人PEA15(星形胶质细胞磷酸化蛋白15)
英文名称：Recombinant Human Phosphoprotein Enriched in Astrocytes of 15 kDa
产品货号：JN0968
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ala130表达纯化得来。

PEA15质量控制：＞95%(还原性SDS-PAGE)

PEA15制剂：冻干品

PEA15保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PEA15复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PEA15：
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm. In addition, PEA15 inhibits both TNFRSF6 and TNFRSF1A mediated CASP8 activity and apoptosis. At present, PEA15 expression is also a significant prognostic marker in ovarian cancer.

我公司销售的重组人PEA15(星形胶质细胞磷酸化蛋白15)，Recombinant Human Phosphoprotein Enriched in Astrocytes of 15 kDa，重组人PEA15，rPEA15，重组Phosphoprotein Enriched in Astrocytes of 15 kDa，重组星形胶质细胞磷酸化蛋白15，重组PEA15，rhPEA15，重组人Phosphoprotein Enriched in Astrocytes of 15 kDa，重组人星形胶质细胞磷酸化蛋白15质量上佳，价格普惠，欢迎广大新老客户踊跃订购。