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- 详细信息
- 技术资料
- 保存条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名:
Cyanoginosin-LR; MC-LR; Toxin T 17 (Microcystis aeruginosa)
- 库存:
货期:询盘
- 供应商:
MedChemExpress LLC
- 规格:
50 μg (0.5 mM * 100 μL in Ethanol)/100 μg (0.5 mM * 200 μL in Ethanol)
| 规格: | 50 μg (0.5 mM * 100 μL in Ethanol) | 产品价格: | ¥2150.0 |
|---|---|---|---|
| 规格: | 100 μg (0.5 mM * 200 μL in Ethanol) | 产品价格: | ¥3650.0 |
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Microcystin-LR
CAS No. : 101043-37-2
MCE 国际站:Microcystin-LR
产品活性:Microcystin-LR 是蛋白磷酸酶 1 型和 2A 型 (PP1/2A) 的有效抑制剂,其 IC50 值分别为 1.7 nM,0.04 nM。
研究领域:Metabolic Enzyme/Protease
作用靶点:Phosphatase
In Vitro: Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.
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